Nunazymes ApS has in 2018 received the EU Horizon2020 SME Instrument Phase 1 grant for the project CLEANprocesses, where we – in collaboration with EY – investigate the potential of our cold-active enzymes in a larger market.

Nunazymes Aps (NZ) is the first Greenlandic biotech company and specializes in the discovery of cold-active enzymes. It holds a patent for the α-amylase AmyI3C6 investigated in the Phase I project. The project studied the technical and commercial feasibility of AmyI3C6. Cold-active enzymes have significant environmental and financial benefits for society, as they optimize production processes and products, leading to savings for producers and consumers. So far, no other company has discovered or lab-engineered enzymes with similar activity levels at the same temperature range as AmyI3C6. AmyI3C6 has shown potential in detergents in terms of cold washing, but the enzyme also has potential in other industries, which were investigated in the project.

The project incl. one work package split into three parts: market analysis, lab testing, and the business plan. The market analysis was performed in two parts: a global market attractiveness study and an in-depth market analysis. The first study investigated seven industries in order to identify those with the most market potential. In addition to detergents, it also found that the beverage and bakery industries are relevant as production processes can be optimized through the usage of cold-active enzymes. The in-depth market analysis focused on these three industries. For detergents, Asia-Pacific had the highest growth rates for cold-active α-amylase. In the beverage and bakery industries, Europe was among the most promising markets. The results feed into the go-to-market logic in the business plan. NZ will create partnerships with enzyme companies from Asia-Pacific and Europe to enter the enzyme market. NZ wants to become the world’s leading cold-active enzyme discovery company, delivering enzyme solutions to other enzyme companies.

Current cold-active α-amylases shows high activity at app. 30ºC. However, with a temperature optimum at 5-20ºC, AmyI3C6 outperforms the existing cold-active α-amylases in the market. AmyI3C6 yields societal implications in the detergent, bakery, and beverage industries, as it can make these industries greener. The environmental impact of cold-active α-amylase in detergent amounts to 0.3 kg of CO2 per 3kg of laundry. Further, if all Danish households reduced laundry temperatures to lukewarm water, annual savings would be EUR 67 mio. For beverages, savings amount to 2.5 kg of CO2 per 100L of beer produced, and for bread, 5.4kg of CO2 per 100 units of white bread. Thus, AmyI3C6 goes far beyond state-of-the-art for cold-active α-amylase.